Research Interests

My interests focus on developing mechanisms by which cell, developmental biologists can adopt, adapt and exploit computational resources to advance their understanding of their biological system of interest. I focus on the utilization of publicly available simulation tools such as Virtual Cell, gfit and other dynamic simulators to understand biological systems at the cellular level. Researchers, educators and students develop the understanding and skills to use modeling, simulation and visualization tools through workshops, short courses and training materials.

Selected Publications

Holmes R. M. and Loew L.M. "Geometry Shapes Cell Signaling Network Output" Chemistry & Biology, June, 2008 doi:10.1016/j.physletb.2003.10.071

Holmes R.M. (2007) A Cell Biologist’s Guide to Modeling and Bioinformatics. John Wiley & Sons. New York.

Holmes R. M. and Qureshi M.M. “Performing as Scientists: an improvisational approach to student research and faculty collaboration” BioScene, March 2006.

Holmes R. and Giles R., “Minority Participation in Computational Science.” Computing in Science & Engineering, March/April 2000, p 11-13.