CCAM -Center for Cell Analysis and Modling

Boris Slepchenko		University of Connecticut Health Center
Associate Professor of Cell Biology		Farmington, CT 06030-3505
		Telephone: (860)679-4025
		Fax: (860)679-1039
		email:boris@neuron.uchc.edu

Research Interests
The Virtual Cell Project. Since my emigration to the U.S. in 1996, I have been working on the Virtual Cell project at CCAM. As a member of a "mathematics team" (also J. Schaff (CCAM), Y. S. Choi (UConn, Storrs), and D. Resasco (Yale)), I am responsible for the subproject Mathematical and Physical Analysis of Cell Biological Processes. I am involved in modeling that is required for the experimental subprojects on calcium dynamics and RNA trafficking and for collaborative projects. I also participate in the development and validation of numerical techniques.

Selected Publications
Novak, I. L., Gao, F., Choi, Y.-S., Resasco, D., Schaff, J. C., Slepchenko B. M. 2007. Diffusion on a Curved Surface Coupled to Diffusion in the Volume: Application to Cell Biology. J. Comput. Phys. 226: 1271-1290.

Slepchenko, B. M., Semenova, I., Zaliapin, I., Rodionov V. 2007. Switching of membrane organelles between cytoskeletal transport systems is determined by the regulation of the microtubule-based transport. J. Cell Biol. 179: 635-641.

Rácz, É., Slepchenko, B. M. On sensitivity amplification in intracellular signaling cascades. 2008. Phys. Biol. 5: 036004.

Kraikivski, P., Slepchenko, B. M., Novak, I. L. Actin Bundling: Initiation Mechanisms and Kinetics. 2008. Phys. Rev. Lett. 101: 128102.

Novak, I. L., Kraikivski, P., Slepchenko, B. M. Diffusion in Cytoplasm: Effects of Excluded Volume Due to Internal Membranes and Cytoskeletal Structures. 2009. Biophys. J. 97: 758-767.